Endocrine Abstracts

Background: Measurements of plasma metanephrines provide a sensitive test for diagnosis of pheochromocytoma/paraganglioma (PPGL). However, false positive results can pose a diagnostic dilemma for clinicians. The aim of the study was to determine whether commonly prescribed drugs with potential action on the sympathetic nervous system can falsely elevate plasma free normetanephrine, metanephrine and methoxytyramine.Methods: This retrospective study includ...

Introduction: Currently, it is unclear whether plasma free or 24-hour urinary metanephrines are preferable for diagnosis of pheochromocytoma/paraganglioma (PPGL) in children.Objectives: To investigate whether measurements of plasma free or 24-hour urinary fractionated metanephrines is a reliable test for screening for PPGL in children.Methods: This retrospective study included data from 60 children with and 78 without PPGL. Data in...